Nighttime Eating & binge eating SYNDROME

Curbing the Appetite

TOPIRAMATE / topamax

For unknown causes of Sleep related eating disorders, or SRED, trials from 2 academic institutions suggest that off-label use of topiramate, 25 to 150 mg at bedtime, may be the treatment of choice.  16-18

Start topiramate at 25 mg, and increase in 25-mg increments every 5 to 7 days until the night eating
episodes are eliminated. Paresthesias, visual symptoms, and (rarely) renal calculus are reported side
effects.